Statistics: | ||
Instances | 42.914 | |
Kinases | 299 | |
References | 3.657 | |
Sequences | 11.224 | |
Substrates | 8.698 |
Res. | Pos. | Sequence | Kinase | PMID | Src | Cons. | ELM | Binding Domain | SMART/Pfam | IUPRED score | PDB | P3D Acc. |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S | 24 | RKVGYLRKPKSMHKRFFVLRA | CK2_group | 8349691 | LTP |
1.00 |
- | PH | 0.26 |
1QQG |
44.26% |
|
S | 24 | RKVGYLRKPKSMHKRFFVLRA | PLK1 | 15849359 | LTP |
1.00 |
- | PH | 0.26 |
1QQG |
44.26% |
|
Y | 46 | SEAGGPARLEYYENEKKWRHK | - | 15592455 | HTP |
1.00 |
- | PH | 0.49 |
1QQG |
9.61% |
|
Y | 46 | SEAGGPARLEYYENEKKWRHK | - | 18083107 | HTP |
1.00 |
- | PH | 0.49 |
1QQG |
9.61% |
|
S | 268 | RAMSDEFRPRSKSQSSSNCSN | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.69 |
- | - |
|
S | 270 | MSDEFRPRSKSQSSSNCSNPI | IKK_group | 12351658 | LTP |
1.00 |
YWHAG 14-3-3; YWHAZ 14-3-3 |
- | 0.69 |
- | - |
|
S | 272 | DEFRPRSKSQSSSNCSNPISV | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.67 |
- | - |
|
S | 274 | FRPRSKSQSSSNCSNPISVPL | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.69 |
- | - |
|
S | 307 | VGLTRRSRTESITATSPASMV | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 307 | VGLTRRSRTESITATSPASMV | PKC_delta | 14583092 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 307 | VGLTRRSRTESITATSPASMV | - | 16099428 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 307 | VGLTRRSRTESITATSPASMV | - | 15199052 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 307 | VGLTRRSRTESITATSPASMV | - | 16129690 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 312 | RSRTESITATSPASMVGGKPG | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 312 | RSRTESITATSPASMVGGKPG | - | 11606564 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 312 | RSRTESITATSPASMVGGKPG | - | 15199052 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 323 | PASMVGGKPGSFRVRASSDGE | PKC_zeta | 15516986 | LTP |
0.05 |
- | - | 0.79 |
- | - |
|
S | 323 | PASMVGGKPGSFRVRASSDGE | - | 14583092 | LTP |
0.05 |
- | - | 0.79 |
- | - |
|
S | 323 | PASMVGGKPGSFRVRASSDGE | PKC_zeta | 16129678 | LTP |
0.05 |
- | - | 0.79 |
- | - |
|
S | 341 | DGEGTMSRPASVDGSPVSPST | IKK_group | 12351658 | LTP |
0.96 |
- | - | 0.90 |
- | - |
|
S | 345 | TMSRPASVDGSPVSPSTNRTH | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.90 |
- | - |
|
S | 348 | RPASVDGSPVSPSTNRTHAHR | - | 16020478 | LTP |
1.00 |
- | - | 0.90 |
- | - |
|
S | 348 | RPASVDGSPVSPSTNRTHAHR | - | 18220336 | HTP |
1.00 |
- | - | 0.90 |
- | - |
|
S | 374 | RLHPPLNHSRSIPMPASRCSP | - | 16020478 | LTP |
1.00 |
YWHAG 14-3-3; YWHAZ 14-3-3 |
- | 0.77 |
- | - |
|
S | 527 | LDNRFRKRTHSAGTSPTITHQ | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.82 |
- | - |
|
T | 530 | RFRKRTHSAGTSPTITHQKTP | - | 16020478 | LTP |
1.00 |
- | - | 0.88 |
- | - |
|
S | 531 | FRKRTHSAGTSPTITHQKTPS | IKK_group | 12351658 | LTP |
1.00 |
- | - | 0.89 |
- | - |
|
S | 531 | FRKRTHSAGTSPTITHQKTPS | - | 18220336 | HTP |
1.00 |
- | - | 0.89 |
- | - |
|
S | 574 | SGGRLPGHRHSAFVPTRSYPE | PKC_delta | 15516986 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 574 | SGGRLPGHRHSAFVPTRSYPE | - | 14583092 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
Y | 612 | DSSTLHTDDGYMPMSPGVAPV | - | 15001544 | LTP |
1.00 |
PIK3R1 SH2; PIK3R2 SH2 |
- | 0.81 |
- | - |
|
Y | 612 | DSSTLHTDDGYMPMSPGVAPV | - | 18083107 | HTP |
1.00 |
PIK3R1 SH2; PIK3R2 SH2 |
- | 0.81 |
- | - |
|
S | 616 | LHTDDGYMPMSPGVAPVPSGR | MAPK3 | 15001544 | LTP |
0.18 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 616 | LHTDDGYMPMSPGVAPVPSGR | - | 14769130 | LTP |
0.18 |
MOD_ProDKin_1 |
- | - | 0.82 |
- | - |
S | 629 | VAPVPSGRKGSGDYMPMSPKS | - | 17081983 | HTP |
0.30 |
- | - | 0.82 |
- | - |
|
Y | 632 | VPSGRKGSGDYMPMSPKSVSA | - | 15001544 | LTP |
1.00 |
PIK3R1 SH2; PIK3R2 SH2 |
- | 0.83 |
- | - |
|
Y | 632 | VPSGRKGSGDYMPMSPKSVSA | - | 18083107 | HTP |
1.00 |
PIK3R1 SH2; PIK3R2 SH2 |
- | 0.83 |
- | - |
|
S | 636 | RKGSGDYMPMSPKSVSAPQQI | - | 14769130 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 636 | RKGSGDYMPMSPKSVSAPQQI | - | 16099428 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 636 | RKGSGDYMPMSPKSVSAPQQI | - | 15576463 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 636 | RKGSGDYMPMSPKSVSAPQQI | - | 16123357 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 636 | RKGSGDYMPMSPKSVSAPQQI | - | 17081983 | HTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 639 | SGDYMPMSPKSVSAPQQIINP | - | 14769130 | LTP |
1.00 |
- | - | 0.73 |
- | - |
|
S | 639 | SGDYMPMSPKSVSAPQQIINP | - | 16099428 | LTP |
1.00 |
- | - | 0.73 |
- | - |
|
S | 639 | SGDYMPMSPKSVSAPQQIINP | - | 15576463 | LTP |
1.00 |
- | - | 0.73 |
- | - |
|
S | 639 | SGDYMPMSPKSVSAPQQIINP | - | 16123357 | LTP |
1.00 |
- | - | 0.73 |
- | - |
|
Y | 662 | RHPQRVDPNGYMMMSPSGGCS | - | 15592455 | HTP |
1.00 |
Fyn SH2; MATK SH2; PIK3R1 SH2; PTPN11 SH2 |
- | 0.77 |
- | - |
|
S | 794 | ARHQHLRLSTSSGRLLYAATA | SIK | 12624099 | LTP |
1.00 |
- | - | 0.65 |
- | - |
|
S | 794 | ARHQHLRLSTSSGRLLYAATA | AMPK_group | 20135346 | LTP |
1.00 |
- | - | 0.65 |
- | - |
|
S | 892 | QPLLHPPEPKSPGEYVNIEFG | - | 16020478 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
Y | 896 | HPPEPKSPGEYVNIEFGSDQS | - | 11259577 | LTP |
1.00 |
GRB2 SH2; PTPN11 SH2 |
- | 0.76 |
- | - |
|
S | 1078 | GMSAFTRVNLSPNRNQSAKVI | - | 16503154 | LTP |
0.30 |
- | - | 0.60 |
- | - |
|
S | 1101 | DPQGCRRRHSSETFSSTPSAT | PKC_theta | 15364919 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 1101 | DPQGCRRRHSSETFSSTPSAT | - | 17081983 | HTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 1101 | DPQGCRRRHSSETFSSTPSAT | RSK-1 | 17709744 | LTP |
1.00 |
- | - | 0.78 |
- | - |
|
S | 1101 | DPQGCRRRHSSETFSSTPSAT | - | 18220336 | HTP |
1.00 |
- | - | 0.78 |
- | - |
|
T | 1111 | SETFSSTPSATRVGNTVPFGA | - | 18220336 | HTP |
1.00 |
- | - | 0.68 |
- | - |
|
S | 1145 | SEDVKRHSSASFENVWLRPGE | - | 16020478 | LTP |
1.00 |
- | - | 0.61 |
- | - |
|
S | 1222 | GSGESSSTRRSSEDLSAYASI | - | 16020478 | LTP |
0.07 |
- | - | 0.70 |
- | - |
|
S | 1223 | SGESSSTRRSSEDLSAYASIS | - | 16020478 | LTP |
0.11 |
- | - | 0.68 |
- | - |
Substrate: | Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.) | ||||||
---|---|---|---|---|---|---|---|
Seq-ID: | P35569 [Mus musculus] | ||||||
Download: | fasta csv | ||||||
Interaction Network(s): | - | ||||||
External Source(s): | |||||||
MINT Interaction(s): | [show] | ||||||
GO-Terms: | [show]
| ||||||
Conservation: | |||||||
Click on table headers for sorting |
Res. | Pos. | Sequence | Kinase | PMID | Src | Cons. | ELM | Binding Domain | SMART/Pfam | IUPRED score | PDB | P3D Acc. |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S | 3 | MASPPDTDGFSDV | - | 17242355 | HTP |
- | - | - | 0.50 |
- | - |
|
S | 267 | DEFRPRSKSQSSSSCSNPISV | - | 12714600 | LTP |
1.00 |
- | - | 0.66 |
- | - |
|
S | 302 | VGLTRRSRTESITATSPASMV | PKB_group | 11701324 | LTP |
1.00 |
MOD_PKB_1 |
- | - | 0.78 |
- | - |
S | 307 | RSRTESITATSPASMVGGKPG | - | 16055440 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 307 | RSRTESITATSPASMVGGKPG | - | 15994203 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 307 | RSRTESITATSPASMVGGKPG | - | 12714600 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 307 | RSRTESITATSPASMVGGKPG | - | 14998989 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 307 | RSRTESITATSPASMVGGKPG | - | 11160134 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 307 | RSRTESITATSPASMVGGKPG | - | 15314024 | LTP |
1.00 |
- | - | 0.80 |
- | - |
|
S | 318 | PASMVGGKPGSFRVRASSDGE | PKC_group | 16129678 | LTP |
0.05 |
- | - | 0.79 |
- | - |
|
S | 318 | PASMVGGKPGSFRVRASSDGE | PKC_group | 16099431 | LTP |
0.05 |
- | - | 0.79 |
- | - |
|
S | 318 | PASMVGGKPGSFRVRASSDGE | PKC_group | 16055440 | LTP |
0.05 |
- | - | 0.79 |
- | - |
|
S | 324 | GKPGSFRVRASSDGEGTMSRP | - | 17242355 | HTP |
1.00 |
- | - | 0.83 |
- | - |
|
S | 340 | TMSRPASVDGSPVSPSTNRTH | - | 17242355 | HTP |
1.00 |
- | - | 0.90 |
- | - |
|
S | 408 | TSDCLFPRRSSASVSGSPSDG | - | 15485932 | LTP |
1.00 |
- | - | 0.60 |
- | - |
|
Y | 608 | DTSNLHTDDGYMPMSPGVAPV | - | 9395471 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.80 |
- | - |
|
Y | 608 | DTSNLHTDDGYMPMSPGVAPV | - | 15821749 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.80 |
- | - |
|
S | 612 | LHTDDGYMPMSPGVAPVPSNR | - | 15994203 | LTP |
0.18 |
- | - | 0.81 |
- | - |
|
S | 612 | LHTDDGYMPMSPGVAPVPSNR | - | 9395471 | LTP |
0.18 |
- | - | 0.81 |
- | - |
|
S | 612 | LHTDDGYMPMSPGVAPVPSNR | - | 15821749 | LTP |
0.18 |
- | - | 0.81 |
- | - |
|
S | 612 | LHTDDGYMPMSPGVAPVPSNR | - | 10092613 | LTP |
0.18 |
- | - | 0.81 |
- | - |
|
S | 632 | RKGNGDYMPMSPKSVSAPQQI | ROCK2 | 16098829 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 632 | RKGNGDYMPMSPKSVSAPQQI | - | 11287630 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 635 | NGDYMPMSPKSVSAPQQIINP | ROCK2 | 16098829 | LTP |
1.00 |
- | - | 0.72 |
- | - |
|
S | 635 | NGDYMPMSPKSVSAPQQIINP | - | 11287630 | LTP |
1.00 |
- | - | 0.72 |
- | - |
|
S | 635 | NGDYMPMSPKSVSAPQQIINP | - | 15994203 | LTP |
1.00 |
- | - | 0.72 |
- | - |
|
S | 789 | ARHQHLRLSSSSGRLRYTATA | AMPK_group | 11598104 | LTP |
0.03 |
- | - | 0.75 |
- | - |
|
S | 1097 | DTQGCRRRHSSETFSAPTRAG | - | 15364919 | LTP |
1.00 |
- | - | 0.79 |
- | - |
|
S | 1139 | SEDVKRHSSASFENVWLRPGD | - | 17242355 | HTP |
1.00 |
- | - | 0.64 |
- | - |
|
S | 1214 | SNEGNSPRRSSEDLSNYASIS | - | 17242355 | HTP |
1.00 |
- | - | 0.76 |
- | - |
Substrate: | Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.) | ||||||
---|---|---|---|---|---|---|---|
Seq-ID: | P35570 [Rattus norvegicus] | ||||||
Download: | fasta csv | ||||||
Interaction Network(s): | - | ||||||
External Source(s): | |||||||
MINT Interaction(s): | [show] | ||||||
GO-Terms: | [show]
| ||||||
Conservation: | |||||||
Click on table headers for sorting |
Res. | Pos. | Sequence | Kinase | PMID | Src | Cons. | ELM | Binding Domain | SMART/Pfam | IUPRED score | PDB | P3D Acc. |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S | 99 | RDEHFAIAADSEAEQDSWYQA | CK2_group | 8349691 | LTP |
0.11 |
MOD_CK2_1 |
- | PH | 0.28 |
- | medium |
Y | 460 | PARGEEELSNYICMGGKGAST | INSR | 7504175 | LTP |
1.00 |
- | - | 0.58 |
- | medium |
|
T | 502 | GATMGTSPALTGDEAAGAADL | CK2_group | 8349691 | LTP |
0.00 |
MOD_CK2_1 |
- | - | 0.72 |
- | medium |
Y | 608 | DSSNLHTDDGYMPMSPGVAPV | INSR | 7504175 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.79 |
- | medium |
|
Y | 608 | DSSNLHTDDGYMPMSPGVAPV | - | 12220227 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.79 |
- | medium |
|
Y | 608 | DSSNLHTDDGYMPMSPGVAPV | IGF1R | 11572799 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.79 |
- | medium |
|
Y | 608 | DSSNLHTDDGYMPMSPGVAPV | INSR | 11572799 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.79 |
- | medium |
|
Y | 628 | VPSNRKGNGDYMPMSPKSVSA | INSR | 7504175 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.81 |
- | medium |
|
Y | 628 | VPSNRKGNGDYMPMSPKSVSA | IGF1R | 11572799 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.81 |
- | medium |
|
Y | 628 | VPSNRKGNGDYMPMSPKSVSA | INSR | 11572799 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.81 |
- | medium |
|
Y | 658 | RHPQRVDPNGYMMMSPSGSCS | IGF1R | 11572799 | LTP |
1.00 |
- | - | 0.72 |
- | medium |
|
Y | 727 | GGKLLPCTGDYMNMSPVGDSN | IGF1R | 11572799 | LTP |
1.00 |
- | - | 0.60 |
- | medium |
|
S | 789 | ARHQHLRLSSSSGRLRYTATA | AMPK_group | 11598104 | LTP |
0.03 |
- | - | 0.77 |
- | medium |
|
Y | 895 | HPPEPKSPGEYVNIEFGSGQP | INSR | 7504175 | LTP |
1.00 |
GRB2 SH2 | - | 0.80 |
- | medium |
|
Y | 895 | HPPEPKSPGEYVNIEFGSGQP | IGF1R | 8530377 | LTP |
1.00 |
GRB2 SH2 | - | 0.80 |
- | medium |
|
Y | 895 | HPPEPKSPGEYVNIEFGSGQP | INSR | 8530377 | LTP |
1.00 |
GRB2 SH2 | - | 0.80 |
- | medium |
|
Y | 939 | APREETGSEEYMNMDLGPGRR | INSR | 7504175 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.87 |
- | medium |
|
Y | 939 | APREETGSEEYMNMDLGPGRR | IGF1R | 11572799 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.87 |
- | medium |
|
Y | 939 | APREETGSEEYMNMDLGPGRR | INSR | 11572799 | LTP |
1.00 |
PIK3R1 SH2 | - | 0.87 |
- | medium |
|
Y | 987 | TRSVPNSRGDYMTMQIGCPRQ | INSR | 7504175 | LTP |
0.16 |
- | - | 0.64 |
- | medium |
|
Y | 987 | TRSVPNSRGDYMTMQIGCPRQ | IGF1R | 11572799 | LTP |
0.16 |
- | - | 0.64 |
- | medium |
|
Y | 987 | TRSVPNSRGDYMTMQIGCPRQ | INSR | 11572799 | LTP |
0.16 |
- | - | 0.64 |
- | medium |
|
Y | 1172 | AAGGLEKSLNYIDLDLVKDVK | INSR | 7504175 | LTP |
1.00 |
PTPN11 SH2 | - | 0.48 |
- | medium |
|
Y | 1172 | AAGGLEKSLNYIDLDLVKDVK | IGF1R | 11572799 | LTP |
1.00 |
PTPN11 SH2 | - | 0.48 |
- | medium |
|
Y | 1172 | AAGGLEKSLNYIDLDLVKDVK | INSR | 11572799 | LTP |
1.00 |
PTPN11 SH2 | - | 0.48 |
- | medium |
|
Y | 1222 | PRRSSEDLSTYASINFQKQPE | INSR | 7504175 | LTP |
0.09 |
PTPN11 SH2 | - | 0.77 |
- | medium |
|
Y | 1222 | PRRSSEDLSTYASINFQKQPE | - | 12220227 | LTP |
0.09 |
PTPN11 SH2 | - | 0.77 |
- | medium |